glp-1 for women Nourish & Thrive: A Dietitian’s Guide to Support Over 40 GLP-1 : Does It Really

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The SELECT trial (N=17,604) added a cardiovascular dimension: semaglutide 2.4 mg reduced major adverse cardiovascular events by 20% versus placebo in adults with overweight or obesity and established cardiovascular disease, over a mean follow-up of 34.2 months [6]

Additionally, lipoic acid increased mitochondrial biogenesis through triggering AMP-activated protein kinase (AMPK)-induced transcription factor PGC-1 activation in skeletal muscle of aged mice (48)

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Up to 40 percent of weight loss from GLP-1s can come from muscle and bone loss